Description

4-(5-Chloro-2-Fluorophenyl)-1,3-Thiazol-2-Amine is a high-purity, heterocyclic organic compound featuring a thiazole core substituted with a chlorinated and fluorinated phenyl ring. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing new pesticides, herbicides, and fungicides due to its bioactive thiazole scaffold.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transport material or a core structure for emissive layer components in electronic displays.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and other functional materials requiring specific aromatic heterocycles.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	4-(5-Chloro-2-Fluorophenyl)-1,3-Thiazol-2-Amine
CAS No.	1202679-25-1
Molecular Formula	C9H6ClFN2S
Molecular Weight	228.67 g/mol
Synonyms	2-Amino-4-(5-chloro-2-fluorophenyl)thiazole; 4-(5-Chloro-2-fluorophenyl)-2-thiazolamine; 4-(5-Chloro-2-fluorophenyl)-1,3-thiazol-2-amine; 5-Chloro-2-fluorophenyl thiazol-2-amine; 2-Thiazolamine, 4-(5-chloro-2-fluorophenyl)-; 1202679-25-1; 4-(5-Chloro-2-fluorophenyl)thiazol-2-amine
EINECS	Contact for details

Quality Control

Our production of 4-(5-Chloro-2-Fluorophenyl)-1,3-Thiazol-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.