Description

4-(Trifluoromethyl)-2,3-Dihydro-1H-Inden-1-Ol is a high-value fluorinated indane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a secondary alcohol, makes it indispensable for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, where precise stereochemistry and purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Asymmetric Catalysis: Employed as a ligand precursor or a substrate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance and unique optical properties.

Basic Information

Product Name	4-(Trifluoromethyl)-2,3-Dihydro-1H-Inden-1-Ol
CAS No.	1202577-87-4
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-Hydroxy-4-(trifluoromethyl)indane; 4-(Trifluoromethyl)indan-1-ol; 1-Indanol, 4-(trifluoromethyl)-; α,α,α-Trifluoro-4-indanemethanol; 4-(Trifluoromethyl)-1-indanol; (4-Trifluoromethyl-2,3-dihydro-1H-inden-1-yl)oxy
EINECS	Contact for details

Quality Control

We supply 4-(Trifluoromethyl)-2,3-Dihydro-1H-Inden-1-Ol in high-purity grades suitable for demanding research and scale-up applications. Our quality assurance is built on rigorous analytical testing including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet your specifications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all critical parameters. We adhere to cGMP principles where required, ensuring traceability and consistency for regulated industry use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.