Description

5-(6-Chloro-1-Methyl-Indol-2-Yl)Nicotinaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-nicotinaldehyde hybrid structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for probing biological mechanisms and target validation in early-stage drug discovery.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	5-(6-Chloro-1-Methyl-Indol-2-Yl)Nicotinaldehyde
CAS No.	1202551-93-6
Molecular Formula	C16H11ClN2O
Molecular Weight	282.72 g/mol
Synonyms	5-(6-Chloro-1-methyl-1H-indol-2-yl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 5-(6-chloro-1-methyl-1H-indol-2-yl)-; 5-(6-Chloro-1-methylindol-2-yl)nicotinaldehyde; 5-(6-Chloro-1-methyl-1H-indol-2-yl)nicotinaldehyde; 1202551-93-6; 5-(6-Chloro-1-methyl-indol-2-yl)-nicotinaldehyde
EINECS	Contact for details

Quality Control

Our production of 5-(6-Chloro-1-Methyl-Indol-2-Yl)Nicotinaldehyde adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.