Description

4'-Ethynyl-[1,1'-Biphenyl]-4-Ol is a high-purity, functionalized biphenyl derivative featuring both a terminal alkyne and a phenolic hydroxyl group. This unique bifunctional structure makes it a versatile and valuable building block in advanced organic synthesis, particularly for the construction of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a core building block for advanced electronic and display materials due to its rigid biphenyl backbone and functional handles.
• Polymer & Dendrimer Chemistry: Enables the synthesis of specialty polymers, cross-linkers, and dendritic structures via click chemistry (e.g., CuAAC) and other coupling reactions.
• Metal-Organic Framework (MOF) Linker: The ethynyl and hydroxyl groups allow for coordination and post-synthetic modification in porous material design.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic and medicinal chemistry.

Basic Information

Item	Details
Product Name	4'-Ethynyl-[1,1'-Biphenyl]-4-Ol
CAS No.	1202355-37-0
Molecular Formula	C14H10O
Molecular Weight	194.23 g/mol
Synonyms	4-(4-Hydroxyphenyl)phenylacetylene; 4'-Ethynylbiphenyl-4-ol; 4-(4-Ethynylphenyl)phenol; 4-Hydroxy-4'-ethynylbiphenyl; [1,1'-Biphenyl]-4-ol, 4'-ethynyl-; Biphenyl-4-ol, 4'-ethynyl-; 4-Ethynyl-4'-hydroxybiphenyl
EINECS	Contact for details

Quality Control

Our 4'-Ethynyl-[1,1'-Biphenyl]-4-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.