Description

2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Propanoate CAS NO 1201657-32-0 is a specialized boron-containing heterocyclic compound, specifically a pyrazole derivative functionalized with a dioxaborolane (pinacol boronate ester) group. This molecular architecture is of significant value in modern synthetic chemistry, particularly in cross-coupling reactions, due to its role as a versatile and stable organoboron reagent. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key organoboron reagent for the palladium-catalyzed formation of carbon-carbon bonds, essential for constructing biaryl and heteroaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and herbicides that require specific boron-containing heterocycles.
• Material Science & OLED Development: Acts as a building block for creating organic light-emitting diode (OLED) materials and other functional organic electronic components.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and bio-conjugation reagents for studying biological processes.

Basic Information

Product Name	2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Propanoate
CAS No.	1201657-32-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1H-Pyrazole-1-propanoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanoate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanoic acid methyl ester; Pinacol (1-(2-methoxy-2-oxoethyl)-1H-pyrazol-3-yl)boronate; Methyl 3-(pinacolatoboryl)-1H-pyrazole-1-propanoate
EINECS	Contact for details

Quality Control

Our 2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original sealed packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.