Description

4,6-Difluoro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is a high-purity, synthetically valuable organic intermediate in its stable hydrochloride salt form. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. Pharmaceutical R&D teams and fine chemical manufacturers need this material for synthesizing complex molecules targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of complex, fluorinated target molecules.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its specific fluorine-substituted indane structure.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Agrochemical Intermediate: Potential application in the synthesis of advanced, fluorinated agrochemicals and pesticides.

Basic Information

Item	Detail
Product Name	4,6-Difluoro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	1199782-88-1
Molecular Formula	C9H10ClF2N
Molecular Weight	205.63 g/mol
Synonyms	1-Amino-4,6-difluoro-2,3-dihydro-1H-indene hydrochloride; 4,6-Difluoroindan-1-amine hydrochloride; 4,6-Difluoro-2,3-dihydro-1H-inden-1-amine HCl; 1H-Inden-1-amine, 4,6-difluoro-2,3-dihydro-, hydrochloride (1:1); 4,6-Difluoro-1-indanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere or in a desiccator for long-term storage. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.