Description

tert-Butyl 4-(5-Bromo-1H-Indazol-3-Yl)Piperidin-1-Carboxylate is a high-value, heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors seeking to introduce complex indazole-piperidine motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, especially for oncology and CNS disorders.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns.
• Chemical Biology Probes: Employed in the creation of tool compounds for target validation and pathway analysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs offering bespoke synthesis services for clinical trial materials.
• Library Synthesis: Used to generate focused chemical libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	tert-Butyl 4-(5-Bromo-1H-Indazol-3-Yl)Piperidin-1-Carboxylate
CAS No.	1198284-77-3
Molecular Formula	C17H22BrN3O2
Molecular Weight	380.28 g/mol
Synonyms	1-Boc-4-(5-bromo-1H-indazol-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(5-bromo-1H-indazol-3-yl)piperidine; tert-Butyl 4-(5-bromo-1H-indazol-3-yl)-1-piperidinecarboxylate; 4-(5-Bromo-1H-indazol-3-yl)piperidine-1-carboxylic acid tert-butyl ester; 5-Bromo-3-(1-Boc-4-piperidyl)-1H-indazole; BOC-4-(5-Bromo-1H-indazol-3-yl)piperidine; 1198284-77-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Bromo-1H-Indazol-3-Yl)Piperidin-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided to support your regulatory and R&D documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.