Description

tert-Butyl 4-(5-Chloro-1H-Indazol-3-Yl)Piperidin-1-Carboxylate is a high-purity advanced pharmaceutical intermediate featuring a piperidine-indazole core structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel drug candidates for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Core scaffold for the research and development of potential kinase inhibitors due to the indazole pharmacophore.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs in custom synthesis projects.
• Bioconjugation & Probe Synthesis: Can be utilized for creating chemical probes for biological target identification and validation.
• Academic Research: Used in university and institutional labs for chemical biology and drug discovery programs.

Basic Information

Product Name	tert-Butyl 4-(5-Chloro-1H-Indazol-3-Yl)Piperidin-1-Carboxylate
CAS No.	1198284-74-0
Molecular Formula	C17H22ClN3O2
Molecular Weight	335.83 g/mol
Synonyms	1-Boc-4-(5-Chloro-1H-indazol-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(5-chloro-1H-indazol-3-yl)piperidine; 4-(5-Chloro-1H-indazol-3-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(5-chloro-1H-indazol-3-yl)-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 4-(5-chloro-1H-indazol-3-yl)-, 1,1-dimethylethyl ester; 1198284-74-0; 5-Chloro-3-(1-Boc-4-piperidyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Chloro-1H-Indazol-3-Yl)Piperidin-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.