Description

tert-Butyl 4-(6-Fluoro-1H-Indazol-3-Yl)Piperidine-1-Carboxylate CAS NO 1198284-41-1 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core functionalized with a fluorinated indazole moiety. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in kinase inhibitor programs.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Synthesis: Integrated into the production process of complex target molecules for preclinical and clinical development.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes to study biological pathways and target engagement.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-fidelity building blocks.

Basic Information

Product Name	tert-Butyl 4-(6-Fluoro-1H-Indazol-3-Yl)Piperidine-1-Carboxylate
CAS No.	1198284-41-1
Molecular Formula	C17H22FN3O2
Molecular Weight	319.38 g/mol
Synonyms	1-Boc-4-(6-Fluoro-1H-indazol-3-yl)piperidine; 4-(6-Fluoro-1H-indazol-3-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(6-fluoro-1H-indazol-3-yl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(6-fluoro-1H-indazol-3-yl)piperidine; 1198284-41-1; 6-Fluoro-3-(1-Boc-4-piperidyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(6-Fluoro-1H-Indazol-3-Yl)Piperidine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D applications. All material is characterized by advanced analytical techniques including HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.