Description

(2-Aminophenyl)Dimethylphosphine Oxide is a specialized organophosphorus compound featuring both an amine and a phosphine oxide functional group on an aromatic ring. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex ligands and functional materials. It is particularly sought after by researchers and manufacturers in the pharmaceutical and advanced materials sectors for applications requiring precise molecular design.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Catalyst Ligand Precursor: Used to develop sophisticated phosphine-based ligands for transition metal catalysis in fine chemical synthesis.
• Material Science Research: Serves as a monomer or additive in the development of advanced polymers, coatings, and flame retardants.
• Agrochemical Synthesis: Intermediate in the creation of new-generation herbicides and plant growth regulators.
• Coordination Chemistry: Chelating agent for metal ions, useful in extraction processes and the preparation of metal-organic frameworks (MOFs).
• Organic Electronics: Potential precursor for electron-transport materials or modifiers in OLED and semiconductor applications.

Basic Information

Product Name	(2-Aminophenyl)Dimethylphosphine Oxide
CAS No.	1197953-47-1
Molecular Formula	C8H12NOP
Molecular Weight	169.16 g/mol
Synonyms	2-(Dimethylphosphinyl)aniline; N-(Dimethylphosphinyl)-2-aminobenzene; Dimethyl(2-aminophenyl)phosphine oxide; (2-Amino-phenyl)-dimethyl-phosphine oxide; o-Aminophenyldimethylphosphine oxide
EINECS	Contact for details

Quality Control

Our (2-Aminophenyl)Dimethylphosphine Oxide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.