Description

4Z,7Z,10Z,13Z,16Z,19Z-Docosahexaenoic-21,21,22,22,22-D5 Acid is a deuterium-labeled analog of the essential ω-3 fatty acid DHA (docosahexaenoic acid). This stable isotope-labeled compound is critical for use as an internal standard in quantitative mass spectrometry, enabling precise measurement of DHA levels in complex biological matrices. It is an indispensable tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and clinical diagnostics industries.

Application

• Internal Standard for Analytical Chemistry: Primary use as a quantitative reference standard in LC-MS/MS and GC-MS analysis of DHA in oils, supplements, and biological samples (plasma, serum, tissues).
• Pharmaceutical Research & Development: Enables accurate pharmacokinetic and metabolic studies of DHA-containing drug formulations and investigational new drugs.
• Nutraceutical & Food Science QC: Ensures assay accuracy and label claim verification for ω-3 supplements, infant formula, and functional foods.
• Clinical Diagnostics: Used in developing and validating high-precision assays for measuring fatty acid profiles in patient samples for research purposes.
• Metabolic Tracer Studies: Facilitates advanced research into the biochemical pathways, turnover, and incorporation of DHA in vivo.
• Reference Material Production: Serves as a key component in the preparation of certified reference materials (CRMs) for laboratory proficiency testing.

Basic Information

Product Name	4Z,7Z,10Z,13Z,16Z,19Z-Docosahexaenoic-21,21,22,22,22-D5 Acid
CAS No.	1197205-71-2
Molecular Formula	C22H27D5O2
Molecular Weight	337.55 g/mol (approx.)
Synonyms	DHA-d5; Docosahexaenoic Acid-d5; all-cis-4,7,10,13,16,19-Docosahexaenoic-21,21,22,22,22-d5 Acid; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic-21,21,22,22,22-d5 Acid; 22:6(n-3)-d5; 22:6ω3-d5; cis-4,7,10,13,16,19-Docosahexaenoic Acid-d5; Deuterated DHA
EINECS	Contact for details

Quality Control

Every batch of our deuterated DHA is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical applications. Comprehensive testing includes assay, isotopic enrichment, and identification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 98.0% (chemical purity)
Isotopic Enrichment	≥ 98 atom % D
Solubility	Soluble in ethanol, DMSO, chloroform; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.