Description

n-Pivaloyl-4-Bromoindole CAS NO 1196981-04-0 is a high-purity, advanced pharmaceutical intermediate characterized by its specific indole ring substitution. This compound is a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) and complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex heterocyclic systems.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and pesticides with novel modes of action.
• Material Science: Investigated for the creation of organic electronic materials and functional dyes due to its indole core structure.
• Academic & R&D: Employed in university and contract research laboratories for methodological studies and the exploration of new chemical entities.

Basic Information

Product Name	n-Pivaloyl-4-Bromoindole
CAS No.	1196981-04-0
Molecular Formula	C₁₃H₁₄BrNO
Molecular Weight	280.16 g/mol
Synonyms	4-Bromo-1-(2,2-dimethylpropanoyl)indole; 4-Bromo-1-pivaloylindole; 1-Pivaloyl-4-bromoindole; 4-Bromoindole-1-carboxylic acid tert-butyl ester; 4-Bromo-1H-indole-1-carboxylic acid, 2,2-dimethyl-1-oxopropyl ester; 1196981-04-0; tert-Butyl 4-bromo-1H-indole-1-carboxylate (common misnomer); 4-Bromo-N-(tert-butylcarbonyl)indole
EINECS	Contact for details

Quality Control

Our n-Pivaloyl-4-Bromoindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.