Description

tert-Butyl 3-Amino-6-Isopropyl-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrazole chemical class. This compound is a critical building block in modern medicinal chemistry, valued for its unique heterocyclic scaffold that enables the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of novel compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Drug Development: Serves as a core structure for developing potential kinase inhibitors and other targeted cancer therapies.
• CNS-Active Compound Synthesis: Employed in the research and development of potential neuropharmaceuticals due to its privileged heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and scale-up activities.
• Process Chemistry & Route Scouting: Used in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	tert-Butyl 3-Amino-6-Isopropyl-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxylate
CAS No.	1196155-07-3
Molecular Formula	C13H22N4O2
Molecular Weight	266.34 g/mol
Synonyms	1H-Pyrrolo[3,4-c]pyrazole-5(4H)-carboxylic acid, 3-amino-4,6-dihydro-6-(1-methylethyl)-, 1,1-dimethylethyl ester; tert-Butyl 3-amino-6-(propan-2-yl)-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxylate; 3-Amino-6-isopropyl-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester; BOC-protected 3-amino-6-isopropylpyrrolopyrazole; 1196155-07-3; tert-Butyl 3-amino-6-isopropyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-6-Isopropyl-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.