Description

4,4-Difluorocyclohexane-1-Sulfonyl Chloride is a high-purity, reactive organofluorine building block used in advanced chemical synthesis. This compound is valued for its role as a versatile sulfonylation reagent, enabling the introduction of the sulfonyl chloride functional group into complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with enhanced efficacy.
• Material Science: Serves as a precursor for creating specialized polymers and surfactants with unique surface properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4,4-Difluorocyclohexane-1-Sulfonyl Chloride
CAS No.	1196154-77-4
Molecular Formula	C6H9ClF2O2S
Molecular Weight	210.65 g/mol
Synonyms	4,4-Difluorocyclohexanesulfonyl Chloride; 1-Sulfonylchloride-4,4-difluorocyclohexane; Cyclohexanesulfonyl chloride, 4,4-difluoro-; 4,4-Difluorocyclohexylsulfonyl Chloride; 1196154-77-4; 4,4-Difluoro-1-cyclohexanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4,4-Difluorocyclohexane-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.