Description

2-Amino-3,3,3-Trifluoropropan-1-Ol Hydrochloride is a high-purity, organofluorine building block essential for advanced chemical synthesis. This compound matters for its trifluoromethyl and amino alcohol functionalities, which are critical for modulating the physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated drug candidates, including protease inhibitors and CNS-active compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Material Science: Incorporated into specialty polymers and advanced materials to impart unique surface properties and chemical resistance.
• Peptide Mimetics: Employed in the design and synthesis of fluorinated peptide analogs for biochemical studies.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and compound libraries.

Basic Information

Product Name	2-Amino-3,3,3-Trifluoropropan-1-Ol Hydrochloride
CAS No.	1196154-75-2
Molecular Formula	C₃H₇ClF₃NO
Molecular Weight	177.54 g/mol
Synonyms	2-Amino-3,3,3-trifluoropropan-1-ol HCl; 3,3,3-Trifluoroalaninol Hydrochloride; 1-Amino-3,3,3-trifluoro-2-propanol Hydrochloride; (RS)-2-Amino-3,3,3-trifluoropropan-1-ol Hydrochloride; (±)-2-Amino-3,3,3-trifluoropropanol Hydrochloride; 3,3,3-Trifluoro-2-aminopropan-1-ol Hydrochloride; 2-Amino-1-hydroxy-3,3,3-trifluoropropane Hydrochloride; 3,3,3-Trifluoro-1-aminopropan-2-ol Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-3,3,3-Trifluoropropan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.