Description

tert-Butyl 6-(Aminomethyl)-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is a high-purity, protected amine derivative belonging to the tetrahydroisoquinoline class of organic compounds. This advanced pharmaceutical intermediate is critical for the synthesis of complex bioactive molecules, offering a versatile handle for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Peptidomimetic Synthesis: Acts as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying enzyme function and receptor interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 6-(Aminomethyl)-3,4-Dihydroisoquinoline-2(1H)-Carboxylate
CAS No.	1196154-55-8
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	Boc-6-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline; 2-(tert-Butoxycarbonyl)-6-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline; 6-(Aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester; tert-Butyl 6-(aminomethyl)-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate; 2-Boc-6-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline; 6-(Aminomethyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-(Aminomethyl)-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP standards ensures the material is suitable for use in advanced research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.