Description

1-Chloro-8-(Trifluoromethyl)Isoquinoline is a high-purity, halogenated isoquinoline derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering a unique trifluoromethyl and chloro substitution pattern that is highly sought after in modern research. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials research organizations seeking to incorporate fluorine-containing motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Ligand Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) influenced by fluorine atoms.

Basic Information

Product Name	1-Chloro-8-(Trifluoromethyl)Isoquinoline
CAS No.	1196152-92-7
Molecular Formula	C10H5ClF3N
Molecular Weight	231.60 g/mol
Synonyms	8-(Trifluoromethyl)-1-chloroisoquinoline; 1-Chloro-8-trifluoromethylisoquinoline; Isoquinoline, 1-chloro-8-(trifluoromethyl)-; 1-Chloro-8-(trifluoromethyl)isoquinoline; 1196152-92-7
EINECS	Contact for details

Quality Control

Our 1-Chloro-8-(Trifluoromethyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.