Description

7-(Trifluoromethyl)Isoquinolin-1-Amine CAS NO 1196147-73-5 is a high-value, fluorinated isoquinoline derivative serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted aromatic structure makes it an essential intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science: Building block for creating advanced organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Ligand Synthesis: Serves as a starting material for constructing complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable substrate for further functionalization and exploration in fluorine chemistry due to the reactive amine group adjacent to the electron-deficient ring system.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	7-(Trifluoromethyl)Isoquinolin-1-Amine
CAS No.	1196147-73-5
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	1-Amino-7-(trifluoromethyl)isoquinoline; 7-(Trifluoromethyl)-1-isoquinolinamine; 1-Isoquinolinamine, 7-(trifluoromethyl)-; 7-Trifluoromethylisoquinolin-1-amine; 1196147-73-5; 7-(Trifluoromethyl)isoquinolin-1-ylamine
EINECS	Contact for details

Quality Control

Every batch of 7-(Trifluoromethyl)Isoquinolin-1-Amine is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.