Description

3-Formyl-4-Nitro-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both formyl and nitro functional groups protected by a tert-butyl ester, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and dyes.
• Academic & Discovery Chemistry: Essential reagent for methodological studies, library synthesis, and exploring new chemical spaces in heterocyclic chemistry.
• Peptidomimetics & Bioconjugation: The reactive aldehyde group enables its use in creating peptide analogs and bioconjugates for biochemical probes.

Basic Information

Product Name	3-Formyl-4-Nitro-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1195785-11-5
Molecular Formula	C₁₄H₁₄N₂O₅
Molecular Weight	290.27 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-formyl-4-nitro-1H-indole; tert-Butyl 3-formyl-4-nitro-1H-indole-1-carboxylate; 4-Nitro-1H-indole-1-carboxylic acid, 3-formyl-, 1,1-dimethylethyl ester; 3-Formyl-4-nitroindole-1-carboxylic acid tert-butyl ester; BOC-3-formyl-4-nitroindole; 1-Boc-3-formyl-4-nitroindole
EINECS	Contact for details

Quality Control

Our 3-Formyl-4-Nitro-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.