Description

1,3(2H)-Pyridinedicarboxylic Acid, 5,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, 1-(1,1-Dimethylethyl) 3-Ethyl Ester is a high-value, multi-functional boronic ester derivative designed for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for the development of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex molecules.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those containing functionalized dihydropyridine cores.
• Agrochemical Synthesis: Employed in creating novel pesticides and herbicides with specific biological activity.
• Material Science Research: Acts as a precursor for organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological processes.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1,3(2H)-Pyridinedicarboxylic Acid, 5,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, 1-(1,1-Dimethylethyl) 3-Ethyl Ester
CAS No.	1194488-90-8
Molecular Formula	C20H30BNO6
Molecular Weight	391.27 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydro-1H-pyridine-1,3(2H)-dicarboxylic acid 1-tert-butyl 3-ethyl ester; tert-Butyl ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1,3-dicarboxylate; 1-(tert-Butyl) 3-ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydro-1H-pyridine-1,3(2H)-dicarboxylate; 4-BPin-1,2,3,6-tetrahydropyridine-1,3-dicarboxylic acid 1-tert-butyl 3-ethyl ester; 1,3-Di-tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1,3-dicarboxylate (common misnomer); Boronic ester derivative of 1,2,3,6-tetrahydropyridine-4-boronic acid.
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Quality Control

Every batch of our 1,3(2H)-Pyridinedicarboxylic Acid, 5,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, 1-(1,1-Dimethylethyl) 3-Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and mass spectrometry results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.