Description

7-(Trifluoromethyl)Isoquinoline is a high-value, fluorinated heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring the isoquinoline core with a trifluoromethyl substituent, makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the trifluoromethyl group imparts improved biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or ligand precursor for creating specialty polymers, organic light-emitting diodes (OLEDs), and liquid crystals.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination, to construct complex molecular architectures.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	7-(Trifluoromethyl)Isoquinoline
CAS No.	1194375-56-8
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	7-(Trifluoromethyl)isoquinoline; Isoquinoline, 7-(trifluoromethyl)-; 7-Trifluoromethylisoquinoline; 7-CF3-Isoquinoline; 7-(Trifluoromethyl)isoquinoline, 98%; 7-(Trifluoromethyl)isoquinoline, 95%; 7-(Trifluoromethyl)isoquinoline, 97%; 7-(Trifluoromethyl)isoquinoline, 99%
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.