Description

R-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate is a specialized chiral organophosphorus compound of significant interest in advanced synthetic chemistry. Its value lies in its utility as a high-performance ligand or catalyst precursor for asymmetric transformations, enabling the production of enantiomerically pure intermediates. This product is essential for R&D and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions such as hydrogenation, cross-coupling, and hydroformylation.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of complex molecular scaffolds in active pharmaceutical ingredient (API) development.
• Agrochemical Research: In the synthesis of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Material Science: Potential application as a chiral dopant or building block for advanced polymeric and liquid crystalline materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	R-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate
CAS No.	1193697-61-8
Molecular Formula	C20H23O4P
Molecular Weight	358.37 g/mol
Synonyms	(R)-H8-BINOL phosphate; (R)-Octahydro-1,1'-bi-2-naphthyl dihydrogen phosphate; (R)-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-binaphthalene]-2,2'-diyl bis(dihydrogen phosphate); (R)-H8-BINAP phosphate (common misnomer); Phosphoric acid, (1R)-1,1',2,2',3,3',4,4'-octahydro-[1,1'-binaphthalene]-2,2'-diyl ester; R-H8-BINOL-P; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of R-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Bi-2-Naphthyl Phosphate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider handling under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.