Description

tert-Butyl 1-(Hydroxymethyl)-3-Azabicyclo[4.1.0]Heptane-3-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique bicyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• API Synthesis: Serves as a precursor in the multi-step synthesis of potential active pharmaceutical ingredients with a 3-azabicyclo[4.1.0]heptane core.
• Protease Inhibitor Development: The structural motif is relevant for the development of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 1-(Hydroxymethyl)-3-Azabicyclo[4.1.0]Heptane-3-Carboxylate
CAS No.	1192688-51-9
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	1-(Hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylic acid tert-butyl ester; tert-Butyl 1-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate; 3-Azabicyclo[4.1.0]heptane-3-carboxylic acid, 1-(hydroxymethyl)-, 1,1-dimethylethyl ester; 3-Boc-1-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane; Bicyclo[4.1.0]heptane intermediate
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(Hydroxymethyl)-3-Azabicyclo[4.1.0]Heptane-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with every batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.