Description

4-Chloro-7-Nitro-1H-Indazol-3-Amine is a high-purity, synthetically valuable heterocyclic building block. This compound is critical for research and development in medicinal chemistry, serving as a key intermediate for the synthesis of novel pharmaceutical agents. It is primarily utilized by R&D laboratories and fine chemical manufacturers targeting oncology, kinase inhibition, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and anticancer agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile indazole scaffold.
• Chemical Biology Probes: Serves as a building block for developing tool compounds and probes to study biological pathways and enzyme functions.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-7-Nitro-1H-Indazol-3-Amine
CAS No.	1192263-96-9
Molecular Formula	C7H5ClN4O2
Molecular Weight	212.59 g/mol
Synonyms	4-Chloro-7-nitro-1H-indazol-3-amine; 3-Amino-4-chloro-7-nitro-1H-indazole; 4-Chloro-7-nitro-1H-indazol-3-ylamine; 1H-Indazol-3-amine, 4-chloro-7-nitro-; 4-Chloro-7-nitroindazol-3-amine; 7-Nitro-4-chloro-1H-indazol-3-amine; 4-Chloro-7-nitro-3-aminoindazole
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Nitro-1H-Indazol-3-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.