Description

(R)-3,3'-Bis(3,5-Difluorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral organophosphorus compound, specifically designed as a high-performance ligand for asymmetric catalysis. Its value lies in its ability to impart exceptional enantioselectivity and reactivity in critical transition-metal-catalyzed reactions, enabling the synthesis of complex, single-enantiomer molecules. This product is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• As a privileged chiral ligand for asymmetric hydrogenation reactions.
• Key component in the synthesis of enantiomerically pure pharmaceutical intermediates.
• Catalyst modifier for asymmetric C-C and C-X bond-forming reactions.
• Research and development of novel catalytic systems in academic and industrial laboratories.
• Production of high-value specialty chemicals requiring precise stereochemical control.
• Development of new methodologies in synthetic organic chemistry.

Basic Information

Product Name	(R)-3,3'-Bis(3,5-Difluorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	1191451-23-6
Molecular Formula	C44H24F4O4P2
Molecular Weight	770.60 g/mol
Synonyms	(R)-3,3'-Bis(3,5-difluorophenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-3,3'-Bis(3,5-difluorophenyl)-BINOL phosphate; (R)-3,3'-Bis(3,5-difluorophenyl)-1,1'-bi-2-naphthol hydrogen phosphate; (R)-3,3'-Di(3,5-difluorophenyl)-BINAP phosphate; Difluorophenyl-substituted BINOL phosphate ligand; (R)-DIFLUOROPHENYL-BINOL phosphate; Asymmetric hydrogenation ligand 1191451-23-6; (R)-BINOL derivative phosphate ligand
EINECS	Contact for details

Quality Control

Every batch of our (R)-3,3'-Bis(3,5-Difluorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is produced and tested under strict quality management systems. We guarantee high chemical and chiral purity, with comprehensive analysis including HPLC for assay and enantiomeric excess (ee) determination. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with each shipment to ensure it meets your rigorous R&D and process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage under an inert atmosphere (e.g., argon or nitrogen) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.