Description

1-Piperidinecarboxylic Acid, 4-(4-Boronophenyl)-, 1-(1,1-Dimethylethyl) Ester is a high-value, protected boronic acid derivative designed for advanced synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecules for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the boronic ester functionality allows for the introduction of specific aromatic moieties.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and molecular probes for target identification and validation studies.
• Process Chemistry & Scale-up: Utilized in route scouting and optimization for the commercial-scale production of fine chemicals and active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for methodology development in organic synthesis and catalysis within university and CRO laboratories.

Basic Information

Item	Details
Product Name	1-Piperidinecarboxylic Acid, 4-(4-Boronophenyl)-, 1-(1,1-Dimethylethyl) Ester
CAS No.	1191062-02-8
Molecular Formula	C16H24BNO4
Molecular Weight	305.18 g/mol
Synonyms	4-(4-Boronophenyl)-1-Boc-piperidine-4-carboxylic Acid; tert-Butyl 4-(4-boronophenyl)piperidine-1-carboxylate; 1-Boc-4-(4-boronophenyl)piperidine-4-carboxylic Acid; 4-(4-Boronophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic Acid; 1-(tert-Butoxycarbonyl)-4-(4-boronophenyl)piperidine-4-carboxylic Acid; 4-(4-Boronophenyl)piperidine-1,4-dicarboxylic Acid 1-tert-Butyl Ester; BOC-Piperidine-4-(4-boronophenyl)-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-(4-Boronophenyl)-, 1-(1,1-Dimethyl) Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure high chemical integrity and lot-to-lot consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic (moisture-sensitive) nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.