Description

6-Bromo-4-Iodo-7-Azaindole is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical discovery and materials science. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the 7-azaindole scaffold's privileged structure in drug discovery.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, where halogenated heterocycles often confer desirable biological activity and stability.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) to introduce diverse functional groups.
• Library Synthesis for High-Throughput Screening: Used in parallel and combinatorial chemistry to generate focused libraries of compounds for biological screening campaigns.

Basic Information

Product Name	6-Bromo-4-Iodo-7-Azaindole
CAS No.	1190322-97-4
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	4-Iodo-6-bromo-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-4-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-bromo-4-iodo-; 6-Bromo-4-iodo-7-aza-indole; 7-Azaindole, 6-bromo-4-iodo-; 6-Br-4-I-7AI
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Iodo-7-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.