Description

3-Bromo-4-Azaindole-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated azaindole scaffold. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel, targeted small-molecule therapeutics. It is primarily needed by R&D and production teams in the pharmaceutical, biotechnology, and fine chemical industries for developing kinase inhibitors and other biologically active compounds.

Application

• Key synthetic intermediate for the development of protein kinase inhibitors targeting various oncology and inflammatory pathways.
• Building block in medicinal chemistry for constructing complex heterocyclic scaffolds with potential therapeutic activity.
• Precursor in the research and synthesis of small molecule drug candidates, particularly in early-stage discovery programs.
• Used in process chemistry for the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing routes.
• Valuable reagent for academic and industrial research exploring structure-activity relationships (SAR) in drug design.
• Starting material for the preparation of custom-labeled compounds for metabolic and pharmacokinetic studies.

Basic Information

Product Name	3-Bromo-4-Azaindole-6-Carboxylic Acid
CAS No.	1190322-94-1
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	3-Bromo-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid; 3-Bromo-6-carboxy-4-azaindole; 3-Bromo-1H-1,6-diazaindole-6-carboxylic acid; 3-Bromo-4-aza-1H-indole-6-carboxylic acid; 3-Bromo-4-azaindole-6-carboxylate; 3-Bromo-4-azaindole-6-COOH; 3-Br-4-AI-6-COOH; 1190322-94-1
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Azaindole-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.