Description

3-Nitro-4-Azaindole-6-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific azaindole scaffold. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily sought after by pharmaceutical R&D departments, biotechnology firms, and contract research organizations (CROs) engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Chemical Biology Probes: Serves as a core structure for developing selective chemical probes to study biological pathways.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	3-Nitro-4-Azaindole-6-Carboxylic Acid Methyl Ester
CAS No.	1190322-85-0
Molecular Formula	C9H7N3O4
Molecular Weight	221.17 g/mol
Synonyms	Methyl 3-nitro-1H-pyrrolo[3,2-b]pyridine-6-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic acid, 3-nitro-, methyl ester; 3-Nitro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid methyl ester; 4-Azaindole-6-carboxylic acid, 3-nitro-, methyl ester; 3-Nitro-4-aza-indole-6-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-Azaindole-6-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.