Description

3-Chloro-6-Fluoro-7-Azaindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused-ring structure, featuring strategically placed halogen atoms, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of kinase inhibitors, particularly for oncology and inflammatory disease targets.
• Agrochemical Synthesis: Used as a core scaffold for creating new generations of herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other optoelectronic applications.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research labs for custom synthesis projects requiring specialized halogenated azaindole chemistry.

Basic Information

Product Name	3-Chloro-6-Fluoro-7-Azaindole
CAS No.	1190322-84-9
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	3-Chloro-6-fluoro-1H-pyrrolo[2,3-b]pyridine; 6-Fluoro-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-6-fluoro-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-chloro-6-fluoro-; 7-Azaindole, 3-chloro-6-fluoro-; 3-Cl-6-F-7-Azaindole
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Fluoro-7-Azaindole is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical R&D and production processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.