Description

3-Chloro-5-Cyano-7-Azaindole is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused-ring structure, featuring chlorine and nitrile substituents, makes it a critical intermediate for constructing complex molecular architectures with tailored properties. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Acts as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Dye & Pigment Industry: Utilized as an intermediate for creating specialized heterocyclic dyes and colorants.
• Academic & Contract Research: Serves as a versatile starting material for novel methodological development and discovery chemistry in research institutions and CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	3-Chloro-5-Cyano-7-Azaindole
CAS No.	1190322-46-3
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile; 7-Azaindole-3-chloro-5-carbonitrile; 3-Chloro-5-cyano-1H-pyrrolo[2,3-b]pyridine; 5-Cyano-3-chloro-7-azaindole; 3-Chloro-5-cyano-1H-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 3-chloro-
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Cyano-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.