Description

4-Chloro-5-Methoxy-7-Aza-2-Oxindole is a high-purity, advanced pharmaceutical intermediate belonging to the oxindole class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes for novel compound libraries.
• Kinase Inhibitor Development: A valuable scaffold for constructing potential inhibitors targeting various kinase enzymes implicated in disease pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-5-Methoxy-7-Aza-2-Oxindole
CAS No.	1190322-44-1
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	4-Chloro-5-methoxy-1H-pyrrolo[3,2-b]pyridin-2(3H)-one; 7-Azaoxindole derivative; 4-Chloro-5-methoxy-7-azaindolin-2-one; 1H-Pyrrolo[3,2-b]pyridin-2(3H)-one, 4-chloro-5-methoxy-; 4-Chloro-5-methoxy-3H-pyrrolo[3,2-b]pyridin-2-one; 4-Chloro-5-methoxy-7-azaoxindole; 4-Cl-5-MeO-7-azaoxindole
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methoxy-7-Aza-2-Oxindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP guidelines for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.