Description

5-Hydroxy-7-Aza-2-Oxindole is a high-purity, advanced pharmaceutical intermediate belonging to the oxindole class of heterocyclic compounds. This specialized building block is critical for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potent kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• API Development: Used in the development and scale-up of Active Pharmaceutical Ingredients (APIs) with complex heterocyclic cores.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme mechanisms and signal transduction pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug design.

Basic Information

Product Name	5-Hydroxy-7-Aza-2-Oxindole
CAS No.	1190322-41-8
Molecular Formula	C7H6N2O2
Molecular Weight	150.14 g/mol
Synonyms	5-Hydroxy-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 7-Azaoxindole-5-ol; 5-Hydroxy-7-azaindolin-2-one; 1H-Pyrrolo[2,3-b]pyridin-2(3H)-one, 5-hydroxy-; 5-Hydroxy-7-azaoxindole; 5-Hydroxy-7-azaindole-2-one; 7-Aza-5-hydroxyoxindole; 5-Hydroxy-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-7-Aza-2-Oxindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.