Description

5-Methoxy-3-Nitro-7-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of complex, biologically active molecules, particularly in medicinal chemistry and drug discovery. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries developing novel therapeutics, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for oncology and antiviral drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the construction of potent and selective kinase inhibitors, leveraging the azaindole core's ability to modulate key biological pathways.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for investigating cellular processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and clinical trial materials.

Basic Information

Product Name	5-Methoxy-3-Nitro-7-Azaindole
CAS No.	1190322-31-6
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	5-Methoxy-3-nitro-1H-pyrrolo[2,3-b]pyridine; 3-Nitro-5-methoxy-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-3-nitro-; 5-Methoxy-3-nitro-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 5-methoxy-3-nitro-
EINECS	Contact for details

Quality Control

Every batch of 5-Methoxy-3-Nitro-7-Azaindole is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR and/or NMR), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.