Description

5-Methoxy-7-Aza-2-Oxindole is a high-purity, advanced pharmaceutical intermediate belonging to the oxindole class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small molecule drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Used in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for new chemical entities (NCEs).
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-Methoxy-7-Aza-2-Oxindole
CAS No.	1190322-28-1
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	5-Methoxy-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 5-Methoxy-7-azaindolin-2-one; 7-Aza-5-methoxyoxindole; 1H-Pyrrolo[2,3-b]pyridin-2(3H)-one, 5-methoxy-; 5-Methoxy-7-azaoxindole; 5-Methoxy-7-azaindole-2-one
EINECS	Contact for details

Quality Control

Our 5-Methoxy-7-Aza-2-Oxindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.