Description

3-Bromo-4-(Trifluoromethyl)-5-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromo substituent and a trifluoromethyl group on an azaindole scaffold, enabling precise molecular modifications and the introduction of key physicochemical properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and optimization of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of small molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance bioavailability and metabolic stability.
• Material Science: Acts as a building block for creating specialized organic electronic materials and functional polymers.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	3-Bromo-4-(Trifluoromethyl)-5-Azaindole
CAS No.	1190322-09-8
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	3-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 4-(Trifluoromethyl)-3-bromo-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-4-trifluoromethyl-5-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-4-(trifluoromethyl)-; 5-Azaindole, 3-bromo-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Trifluoromethyl)-5-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.