Description

6-Bromo-3-Iodo-7-Azaindole is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents on the 7-azaindole scaffold, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, cross-coupling reactions, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other biologically active heterocycles.
• Medicinal Chemistry & SAR Studies: Used to explore structure-activity relationships (SAR) by introducing halogen atoms at specific positions on the 7-azaindole core.
• Cross-Coupling Reactions: Serves as a premium substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations due to its reactive halogen handles.
• Agrochemical Research: Employed in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological systems and protein interactions.

Basic Information

Item	Detail
Product Name	6-Bromo-3-Iodo-7-Azaindole
CAS No.	1190321-85-7
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	3-Iodo-6-bromo-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-bromo-3-iodo-; 6-Bromo-3-iodo-7-aza-indole; 6-Br-3-I-7-Azaindole; 6-Bromo-3-iodo-7-azaindole; 3-Iodo-6-bromo-7-azaindole
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Iodo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder/crystals
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.