Description

6-Hydroxy-3-Chloro-5-Azaindole is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in modern synthetic chemistry. Its unique fused-ring structure, featuring both hydroxy and chloro substituents, makes it a versatile building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides due to its bioactive azaindole core.
• Material Science: Building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Synthesis: Versatile scaffold for further functionalization in medicinal and combinatorial chemistry for library generation.
• Academic & Contract Research: Serves as a standard or starting material for methodological studies and custom synthesis projects in university and CRO (Contract Research Organization) labs.

Basic Information

Product Name	6-Hydroxy-3-Chloro-5-Azaindole
CAS No.	1190319-69-7
Molecular Formula	C7H5ClN2O
Molecular Weight	168.58 g/mol
Synonyms	3-Chloro-6-hydroxy-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-1H-pyrrolo[2,3-b]pyridin-6-ol; 5-Azaindole, 6-hydroxy-3-chloro-; 6-Hydroxy-3-chloro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-3-Chloro-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.