Description

3-Amino-5-Trifluoromethyl-4-Azaindole is a high-value, multi-functional heterocyclic building block featuring a unique azaindole scaffold substituted with an amino group and a trifluoromethyl group. This compound matters for its critical role in modern medicinal chemistry, where it serves as a privileged structure for designing novel bioactive molecules. Pharmaceutical and agrochemical research organizations need this intermediate to develop new drug candidates and crop protection agents targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the azaindole core.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and protein functions.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production for client projects.

Basic Information

Product Name	3-Amino-5-Trifluoromethyl-4-Azaindole
CAS No.	1190319-60-8
Molecular Formula	C8H6F3N3
Molecular Weight	201.15 g/mol
Synonyms	3-Amino-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-amine; 3-Amino-5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-3-amine, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-3-amino-4-azaindole; 3-Amino-5-CF3-4-azaindole; 4-Azaindole, 3-amino-5-trifluoromethyl-
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Trifluoromethyl-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.