Description

3-Chloro-6-Trifluoromethyl-4-Azaindole is a high-value, halogenated azaindole derivative, a crucial building block in modern synthetic organic chemistry. Its unique molecular scaffold, featuring both chloro and trifluoromethyl substituents, is engineered to impart significant biological activity and metabolic stability to target molecules. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of small-molecule drugs, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging the bioactivity of the azaindole core.
• Chemical Biology Probe: Serves as a versatile scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a precursor for functional organic materials due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring specialized heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-6-Trifluoromethyl-4-Azaindole
CAS No.	1190319-49-3
Molecular Formula	C8H4ClF3N2
Molecular Weight	220.58 g/mol
Synonyms	3-Chloro-6-(trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine; 6-(Trifluoromethyl)-3-chloro-1H-pyrrolo[3,2-c]pyridine; 3-Chloro-6-trifluoromethyl-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 3-chloro-6-(trifluoromethyl)-; 3-Chloro-6-(trifluoromethyl)-4-azaindole; 3-Chloro-6-trifluoromethyl-4-aza-indole
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Trifluoromethyl-4-Azaindole is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (NMR, MS), and impurity profile, is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.