Description

5-Amino-3-Chloro-4-Azaindole is a high-purity, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its unique fused-ring structure, featuring both amino and chloro substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise chemical functionality is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials and advanced polymers requiring specific nitrogen-containing heterocycles.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex indole and azaindole derivatives.
• Bioconjugation & Probe Development: The reactive amino group allows for functionalization, making it useful in creating fluorescent probes or biochemical tags.

Basic Information

Product Name	5-Amino-3-Chloro-4-Azaindole
CAS No.	1190319-36-8
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridin-5-amine; 3-Chloro-5-amino-1H-pyrrolo[2,3-b]pyridine; 5-Amino-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-azaindol-5-amine; 5-Amino-3-chloro-4-aza-indole; 1H-Pyrrolo[2,3-b]pyridin-5-amine, 3-chloro-; AZD-1 Building Block
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Chloro-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.