Description

4-Bromo-3-Iodo-6-Azaindole is a high-value halogenated azaindole derivative, a crucial heterocyclic building block in modern synthetic chemistry. Its unique structure, featuring both bromine and iodine atoms on the azaindole scaffold, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery, medicinal chemistry, and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to introduce halogen atoms for modulating potency, selectivity, and metabolic stability.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine and iodine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig).
• Chemical Biology: Utilized as a probe or tag in bioconjugation and the development of chemical tools for biological target identification.

Basic Information

Product Name	4-Bromo-3-Iodo-6-Azaindole
CAS No.	1190319-21-1
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	4-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-4-bromo-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-3-iodo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-3-iodo-; 4-Br-3-I-6-Azaindole; 6-Azaindole, 4-bromo-3-iodo-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Iodo-6-Azaindole is manufactured and tested under strict quality management protocols. We guarantee high purity and consistency to meet the exacting standards of research and development. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to ensure identity, purity, and impurity profile. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.