Description

5-Bromo-3-Iodo-4-Azaindole is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical discovery and materials science. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its halogenated indole core.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis for Drug Discovery: A valuable scaffold for generating diverse compound libraries via parallel and combinatorial chemistry techniques.

Basic Information

Product Name	5-Bromo-3-Iodo-4-Azaindole
CAS No.	1190319-16-4
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	5-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-3-iodo-7-azaindole; 5-Bromo-3-iodo-4-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-iodo-; 4-Azaindole, 5-bromo-3-iodo-
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Iodo-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.