Description

3-Chloro-6-Cyano-7-Azaindole is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused-ring structure, featuring chlorine and nitrile substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, including ligands for OLEDs and other optoelectronic applications.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Academic & Contract Research: A valuable reagent for methodological development and novel heterocycle construction in academic and CRO laboratories.

Basic Information

Product Name	3-Chloro-6-Cyano-7-Azaindole
CAS No.	1190318-95-6
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	7-Azaindole-3-carbonitrile, 6-chloro-; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 6-Chloro-7-azaindole-3-carbonitrile; 3-Chloro-6-cyano-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Cyano-7-Azaindole is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 97.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.