Description

3-Amino-4-Chloro-5-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need it for creating targeted drug candidates, especially in oncology and kinase inhibitor research, where its unique fused ring system offers distinct structural advantages.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of new active ingredients for crop protection products.
• Material Science: Serves as a building block for advanced organic electronic materials and functional dyes.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.

Basic Information

Product Name	3-Amino-4-Chloro-5-Azaindole
CAS No.	1190318-73-0
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	4-Chloro-1H-pyrrolo[3,2-c]pyridin-3-amine; 4-Chloro-3-amino-7-azaindole; 4-Chloro-3-amino-1H-pyrrolo[3,2-c]pyridine; 3-Amino-4-chloro-1H-pyrrolo[3,2-c]pyridine; 3-Amino-4-chloro-7-azaindole; 1H-Pyrrolo[3,2-c]pyridin-3-amine, 4-chloro-; 4-Chloro-1H-pyrrolo[3,2-c]pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Chloro-5-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring material that meets ICH Q7 guidelines and other relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.