Description

6-Nitro-4-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its nitro-substituted azaindole heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for oncology and anti-inflammatory applications.
• Kinase Inhibitor Development: Serves as a core scaffold or a functionalized fragment for designing and optimizing potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening campaigns.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme mechanisms and validate novel drug targets.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Material Science: Investigated as a precursor for organic electronic materials due to its electron-deficient aromatic system.

Basic Information

Product Name	6-Nitro-4-Azaindole
CAS No.	1190318-66-1
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	4-Azaindole, 6-nitro-; 6-Nitro-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 6-nitro-; 6-Nitro-4-azaindole; 6-Nitro-1H-4-azaindole; 6-Nitro-4-aza-indole; 6-Nitropyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our 6-Nitro-4-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development and cGMP-grade requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.