Description

7-Chloro-4-Aza-2-Oxindole is a high-purity, synthetically valuable heterocyclic building block, identified by CAS NO 1190318-32-1. This compound is essential for medicinal chemistry research and development, serving as a privileged scaffold for constructing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drug candidates.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Used to develop tool compounds for investigating specific biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical space.

Basic Information

Product Name	7-Chloro-4-Aza-2-Oxindole
CAS No.	1190318-32-1
Molecular Formula	C7H4ClN2O
Molecular Weight	168.57 g/mol
Synonyms	7-Chloro-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one; 7-Chloro-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-one; 7-Chloro-4-azaindolin-2-one; 7-Chloro-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridin-2-one, 7-chloro-1,3-dihydro-; 7-Chloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Aza-2-Oxindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity building blocks for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.