Description

7-Bromo-3-Iodo-6-Azaindole is a high-value halogenated azaindole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and iodine substituents on the azaindole scaffold, makes it an exceptionally versatile building block for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Material Science: Serves as a building block for organic electronic materials and functional dyes due to its electron-rich indole-based structure.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for versatile palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	7-Bromo-3-Iodo-6-Azaindole
CAS No.	1190318-20-7
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	7-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-7-bromo-1H-pyrrolo[2,3-b]pyridine; 7-Bromo-3-iodo-6-aza-indole; 1H-Pyrrolo[2,3-b]pyridine, 7-bromo-3-iodo-; 6-Azaindole, 7-bromo-3-iodo-; 7-Br-3-I-6-AI
EINECS	Contact for details

Quality Control

Every batch of 7-Bromo-3-Iodo-6-Azaindole is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our standard quality commitment ensures the material meets the stringent requirements for research and development applications. Specifications can be tailored to meet specific project needs, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.