Description

6-Methoxy-3-Nitro-4-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its distinct azaindole core structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex, nitrogen-containing heterocycles. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Used in the development and testing of biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale production of potential therapeutic molecules.
• Academic Research: Utilized in university and institutional labs for fundamental studies on heterocyclic chemistry and reaction methodology.

Basic Information

Product Name	6-Methoxy-3-Nitro-4-Azaindole
CAS No.	1190317-64-6
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	3-Nitro-6-methoxy-1H-pyrrolo[3,2-c]pyridine; 6-Methoxy-3-nitro-1H-pyrrolo[3,2-c]pyridine; 4-Azaindole, 6-methoxy-3-nitro-; 1H-Pyrrolo[3,2-c]pyridine, 6-methoxy-3-nitro-; 6-Methoxy-3-nitro-4-aza-indole
EINECS	Contact for details

Quality Control

Our 6-Methoxy-3-Nitro-4-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.