Description

5-Bromo-4-Nitro-7-Azaindole is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other biologically active small molecules.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis Building Block: Serves as a precursor for further functionalization via cross-coupling reactions, nucleophilic substitutions, or reductions.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying enzyme function and cellular signaling pathways.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents.

Basic Information

Product Name	5-Bromo-4-Nitro-7-Azaindole
CAS No.	1190317-07-7
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	4-Nitro-5-bromo-7-azaindole; 5-Bromo-4-nitro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-nitro-; 5-Bromo-4-nitro-1H-7-azaindole; 5-Bromo-4-nitropyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Nitro-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.